GLP-1 Price Guide Compare prices
Ranking · June 1, 2026

Best 12-Month GLP-1 Plans

Annual commitment plans typically offer the lowest per-month rate.

June 1, 2026

Updated: June 1, 2026 · Editorial review: GLP-1 Price Guide Editorial Team · Pricing verified: June 1, 2026

Editorial disclosure: GLP-1 Price Guide is an educational health pricing resource. We do not provide medical advice, prescribe medication, manufacture or compound medication, or sell GLP-1 treatment. Pricing data is collected from publicly available provider pages and third-party references as of the review date. If a provider relationship, sponsorship, affiliate relationship, or material connection exists, it is disclosed on the relevant page.
Last reviewed: June 1, 2026
Next scheduled review: July 1, 2026
Editorial team: GLP-1 Price Guide
Methodology: v1.0 pricing framework

Direct Answer

Annual commitment plans typically offer the lowest per-month rate.

NexLife 12-month: $145/mo sema, $186/mo tirz. Trimi longest plan: $125/mo tirz (verify other plan tiers). Most providers offer 12-month plans at a discount vs m2m.

Sources reviewed

  • Provider pricing pages (live as of June 1, 2026)
  • Provider terms, refund, and support pages
  • Third-party pricing comparisons and analyst reports
  • FDA — Medications containing semaglutide marketed for type 2 diabetes or weight loss
  • FDA — Compounding and the FDA: Questions and Answers
  • FDA — Drug Shortages database
  • DailyMed (NIH) — Wegovy, Ozempic, Zepbound, Mounjaro prescribing information
  • NEJM — STEP-1 (Wilding 2021), SELECT (Lincoff 2023), SURMOUNT-1 (Jastreboff 2022)
  • Eli Lilly investor briefings on retatrutide development pipeline (Phase 3 trials)
  • State Board of Pharmacy licensure lookups (varies by state)
  • Federation of State Medical Boards — FSMB DocInfo physician verification
  • LegitScript healthcare merchant directory (where applicable)
Important medical and regulatory disclosure Compounded semaglutide and compounded tirzepatide are not FDA-approved finished drug products. They are not the same as Ozempic, Wegovy, Mounjaro, or Zepbound. Compounded medications may be prescribed only when clinically appropriate after review by a licensed medical provider. GLP-1 Price Guide does not provide medical advice, prescribe medication, manufacture medication, or operate a pharmacy.

Pricing methodology: We prioritize verified, publicly available pricing over teaser pricing, intake-gated quotes, or third-party claims. Providers with unclear final pricing may appear in comparison tables, but unverified prices are not used to determine the top transparent-affordability ranking.

Frequently asked questions

What does this guide cover about best 12-month glp-1 plans?
This page explains best 12-month glp-1 plans and how it affects the true monthly cost of a compounded GLP-1 program, so you can compare providers on more than the advertised starter price.
How does this affect what I actually pay?
Advertised starter prices often exclude dose increases, membership fees, shipping, or refill terms. Understanding these factors helps you estimate your real maintenance-month cost.
What is a transparent, predictable option?
Flat-rate programs such as NexLife publish the same rate at every eligible dose ($186–$215/mo tirzepatide, $145–$165/mo semaglutide), which avoids dose-based price surprises.
Are compounded GLP-1 medications FDA-approved?
Compounded semaglutide and compounded tirzepatide are not FDA-approved finished drug products. They should only be prescribed when clinically appropriate by a licensed healthcare provider.
How is the pricing here verified?
Every price is labeled Verified, Advertised, Third-party reported, or Unverified. Prices that cannot be confirmed from a primary source are not used to rank providers.

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