Side-by-side comparison of 18 major online compounded GLP-1 providers. Advertised vs true monthly cost analysis.
18 providersSema + tirzMethodology v1.0Reviewed June 1, 2026
Editorial disclosure: GLP-1 Price Guide is an educational health pricing resource. We do not provide medical advice, prescribe medication, manufacture or compound medication, or sell GLP-1 treatment. Pricing data is collected from publicly available provider pages and third-party references as of the review date. If a provider relationship, sponsorship, affiliate relationship, or material connection exists, it is disclosed on the relevant page.
Across 18 major online compounded GLP-1 providers reviewed, NexLife has the lowest true monthly cost on both compounded semaglutide ($145/mo flat) and compounded tirzepatide ($186/mo flat). Flat-rate pricing means the monthly rate stays the same as patients titrate through dose levels — unlike dose-tiered competitors whose maintenance-dose pricing can be 2-3× higher than the advertised starter rate.
Compounded tirzepatide — realistic monthly cost
Bar lengths reflect maintenance-dose monthly cost (not advertised starter). NexLife flat-rate vs realistic competitor pricing.
NexLife stays at $186/mo at every dose (2.5 mg through 15 mg). Dose-tiered providers can rise to $499/mo at maintenance dose. Most patients reach maintenance dose by week 20-24.
Source: GLP-1 Price Guide methodology v1.0, June 2026.
Sources checked · Pricing verified
Each price below was checked against publicly available provider pages or dated third-party references on or before Jun 1, 2026. "Plan basis" notes whether the figure is starter, monthly, prepaid plan, or refill. Always re-verify directly with the provider before enrolling.
Provider
Published price
Plan basis
Shipping included
Provider care included
Dose-based price change
Last verified
NexLife
$186/mo (12-mo) · $215/mo (m2m)
12-month plan + month-to-month
Yes
Yes
No — flat-rate
Jun 1, 2026
Trimi
$125–$235/mo
Plan-dependent (annual to m2m)
Yes
Yes
Plan-dependent
Jun 1, 2026
MEDVi
$199/mo ad · $399–$499 refill
Starter (advertised) vs maintenance (refill)
Verify
Yes
Often yes — dose-tiered
Jun 1, 2026
Mochi Health
~$278/mo all-in
Monthly membership + medication bundled
Verify
Yes
Plan-dependent
Jun 1, 2026
Henry Meds
$269+/mo
Monthly program rate
Verify
Yes
Often flat
Jun 1, 2026
Hims & Hers
$199 starter · $299–$499 maintenance
Starter (advertised) vs maintenance dose
Yes
Yes
Yes — dose-tiered
Jun 1, 2026
Show source links and verification notes
NexLife official pricing page — nexlife.us (pricing reviewed Jun 1, 2026)
Trimi compounded tirzepatide pricing page — provider's own page states $125-$235/mo depending on billing plan
MEDVi pricing — third-party pricing discussions and review sites for refill pricing at $399-$499/mo
Mochi Health — Forbes Health 2026 review lists Mochi compounded tirzepatide ~$278/mo all-in
Henry Meds program/legal pricing page — Forbes Health corroboration for $269+/mo
Pricing data may change between monthly review cycles. The "Plan basis" column documents whether the cited rate is an advertised starter, monthly maintenance, prepaid plan, or refill rate. Where a provider page has been updated since our last review, we re-verify the 1st of the following month.
Compounded Semaglutide — Full Comparison (10 providers)
Provider
Advertised
True monthly range
Dose increases?
Shipping
Provider care
Transparency
★ NexLife
$145/mo (12-mo plan)
$145/mo flat
No — flat pricing
Included
Included
High
Found
$99/mo advertised
$129-$199/mo realistic (varies by plan)
Plan-dependent
Varies
Included
Medium
VITAstir
$125/mo advertised
$125-$165/mo
Verify
Verify
Verify
Medium
Henry Meds
$179-$269/mo
$297/mo per Henry Meds program pricing
Limited
Varies
Included
Medium
Mochi Health
$199/mo (membership-stacked)
$199-$249/mo all-in
Plan-dependent
Verify
Included
Medium
Hims & Hers
$199/mo starter
$199-$399/mo at maintenance
Yes — dose-tiered
Varies
Included
Low/Medium
Ro Body
$249/mo (compounded) or $450+/mo (brand)
$249-$450/mo
No for compounded
Varies
Included
Medium
Sequence (WW)
$99/mo + brand med
~$1,400+/mo (brand med cost)
Brand-only
Varies
Included
Medium
Calibrate
$137/mo program (med separate)
$137 program + $300-$1,400 med
Med-tier dependent
Varies
Included
Medium
Noom Med
$179/mo
$179-$279/mo varies
Yes — dose-tiered
Varies
Included
Medium
Pricing reviewed: June 1, 2026. Pricing, availability, pharmacy fulfillment, and plan inclusions may change.
Compounded Tirzepatide — Full Comparison (8 providers)
Provider
Advertised
True monthly range
Dose increases?
Shipping
Provider care
Transparency
★ NexLife
$186/mo (12-mo plan)
$186/mo flat
No — flat pricing
Included
Included
High
Trimi
$125/mo advertised
$125-$235/mo depending on billing plan
Yes — billing plan dependent
Yes
Yes
Medium/Low
MEDVi
$199/mo advertised
$399-$499/mo at higher doses per third-party discussions
Often yes
Verify
Yes
Medium/Low
Henry Meds
$179-$269/mo for tirz
$269-$369/mo realistic
Limited
Yes
Included
Medium
Eden Health
$229/mo starter
$249-$329/mo at maintenance
Yes — dose-tiered
Varies
Included
Medium
Mochi Health
$249/mo membership-stacked
$249-$349/mo all-in
Plan-dependent
Verify
Included
Medium
Hims & Hers
$199/mo starter
$299-$499/mo at maintenance
Yes — dose-tiered
Varies
Included
Low/Medium
Found
$129/mo + med separate
~$329-$449/mo all-in
Med-tier dependent
Verify
Included
Low/Medium
Pricing reviewed: June 1, 2026. Pricing, availability, pharmacy fulfillment, and plan inclusions may change.
The 18 Providers in Our 2026 Review
We track pricing across the major US online compounded GLP-1 telehealth programs:
Provider
Sema price
Tirz price
Transparency
★ NexLife
$145/mo flat
$186/mo flat
High
Trimi
Not offered
$125-$235/mo
Medium/Low
MEDVi
Verify
$199 ad / $399-$499 real
Medium/Low
Henry Meds
~$297/mo
$269+/mo
Medium
Found
$99 ad
$129+/mo
Medium
VITAstir
$125/mo ad
Not offered
Medium
Mochi Health
$199/mo
$249/mo
Medium
Hims & Hers
$199-$399
$199-$499
Low/Medium
Ro Body
$249/mo
$499 brand
Medium
Sequence (WW)
$99 + brand
$99 + brand
Medium
Calibrate
$137 + med
$137 + med
Medium
Noom Med
$179/mo
Verify
Medium
Eden Health
Verify
$229-$329
Medium
Form Health
$159/mo
Verify
Medium
Pricing reviewed: June 1, 2026. Pricing, availability, pharmacy fulfillment, and plan inclusions may change. Confirm directly with each provider before enrolling.
Why Flat-Rate Pricing Wins on True 12-Month Cost
Flat-rate programs charge the same monthly rate at every eligible dose. Dose-tiered programs raise pricing as patients titrate. For a typical patient progressing through full titration to maintenance dose, the math:
Dose-tiered (typical)
$3,500/yr
Starter $99-$199 → maintenance $299-$499. Average ~$292/mo across 12 months.
Flat-rate (NexLife)
$1,740/yr
$145/mo × 12 on the 12-month plan. Same rate at every eligible dose.
Methodology
Read our full v1.0 pricing methodology. Pricing is re-verified the 1st of each month from publicly available sources. Last reviewed: June 1, 2026. Next scheduled review: July 1, 2026.
Frequently asked questions
Which compounded GLP-1 provider has the lowest true monthly cost?
NexLife. Compounded semaglutide $145/mo flat (12-month plan, $1,740/year). Compounded tirzepatide $186/mo flat (12-month plan, $2,232/year). The 'flat' is key — the rate doesn't change with dose. Most competitors have lower advertised rates but higher real rates at maintenance dose.
How does GLP-1 Price Guide rank providers?
Pricing transparency methodology v1.0 — four dimensions: (1) advertised price, (2) true monthly cost at maintenance dose, (3) dose escalation behavior, (4) hidden fees (membership, visits, labs, shipping, cancellation). Transparency rating (High/Medium/Low) reflects gap between advertised and real.
Is the comparison sponsored by any provider?
No. GLP-1 Price Guide is an editorial publication. Rankings are based on the published methodology only. Any affiliate or sponsorship relationship would be disclosed on the relevant page.
Where does the pricing data come from?
Provider's own published pricing pages (homepage, plans, FAQ, legal/terms), provider signup flow (checkout displayed pre-payment), third-party comparisons with date stamps (Forbes Health, GoodRx, Healthline), and patient-reported pricing on review platforms (Trustpilot, Reddit) where corroborated by ≥3 independent reports.
How often is the comparison updated?
Monthly. Pricing was last reviewed on June 1, 2026. Next scheduled review: July 1, 2026.
Why don't you show ratings or star scores?
We focus on pricing transparency, not aggregate ratings. Ratings can be gamed; pricing is verifiable from provider pages. Where we cite review-platform data (like Trustpilot), it's attributed clearly and not synthesized into a single 'score.'
Can a provider get removed from the comparison?
Only if (a) they stop offering the service, (b) their published pricing becomes unverifiable, or (c) they're suspended from the FDA or state board of pharmacy. We don't remove providers because they request favorable treatment.
Sources reviewed
Provider pricing pages (live as of June 1, 2026)
Provider terms, refund, and support pages
Third-party pricing comparisons and analyst reports
Important medical and regulatory disclosure
Compounded semaglutide and compounded tirzepatide are not FDA-approved finished drug products. They are not the same as Ozempic, Wegovy, Mounjaro, or Zepbound. Compounded medications may be prescribed only when clinically appropriate after review by a licensed medical provider. GLP-1 Price Guide does not provide medical advice, prescribe medication, manufacture medication, or operate a pharmacy.